Construction and performance of the BABAR-DIRC

The new type of ring-imaging Cherenkov detector technology called DIRC (an acronym for Detection of Internally Reflected Cherenkov (Light)) has been used successfully for hadronic particle identification in the BABAR experiment at the B Factory (PEP-II) located at the SLAC National Accelerator Laboratory. This paper describes the R&D for and the construction of the DIRC radiator bars and the performance of the DIRC during more than eight years of B Factory operation

DIRC, the Internally Reflecting Ring Imaging Cherenkov Detektor for BaBar: Properties of the Quartz Radiators

The DIRC is a Cherenkov imaging detector based on total internal reflection for the BaBar detector at PEP-II. The principles of the DIRC ring imaging Cherenkov technique are explained and its choice for the BaBar detector particle identification system is motivated. The detector design and the status of the R&D are discussed. Results of the measurement of the optical properties and radiation damage of the the radiators, long rectangular bars made of synthetic fused silica, are presented.Comment: 4 pp. Contributed to the 7th ICFA School on Instrumentation in Elementary Particle Physics, Leon, Guanajuato, Mexico, 7-19 Jul 199

Optical Properties of the DIRC Fused Silica Cherenkov Radiator

The DIRC is a new type of Cherenkov detector that is successfully operating as the hadronic particle identification system for the BABAR experiment at SLAC. The fused silica bars that serve as the DIRC's Cherenkov radiators must transmit the light over long optical pathlengths with a large number of internal reflections. This imposes a number of stringent and novel requirements on the bar properties. This note summarizes a large amount of R&D that was performed both to develop specifications and production methods and to determine whether commercially produced bars could meet the requirements. One of the major outcomes of this R&D work is an understanding of methods to select radiation hard and optically uniform fused silica material. Others include measurement of the wavelength dependency of the internal reflection coefficient, and its sensitivity to surface contaminants, development of radiator support methods, and selection of good optical glue.Comment: 36 pages, submitted to Nuclear Instruments and Methods

Acute atrial arrhythmogenesis in murine hearts following enhanced extracellular Ca2+ entry depends on intracellular Ca2+ stores

Aim To investigate the effect of increases in extracellular Ca2+ entry produced by the L-type Ca2+ channel agonist FPL-64176 (FPL) upon acute atrial arrhythmogenesis in intact Langendorff-perfused mouse hearts and its dependence upon diastolic Ca2+ release from sarcoplasmic reticular Ca2+ stores. Methods: Confocal microscope studies of Fluo-3 fluorescence in isolated atrial myocytes were performed in parallel with electrophysiological examination of Langendorff-perfused mouse hearts. Results: Atrial myocytes stimulated at 1 Hz and exposed to FPL (0.1 μm) initially showed (10 min) this reverted to a regular pattern of evoked transients with increased amplitudes but in which diastolic peaks were absent. Higher FPL concentrations (1.0 μm) produced sustained and irregular patterns of cytosolic Ca2+ activity, independent of pacing. Nifedipine (0.5 μm), and caffeine (1.0 mm) and cyclopiazonic acid (CPA) (0.15 μm) pre-treatments respectively produced immediate and gradual reductions in the F/F0 peaks. Such nifedipine and caffeine, or CPA pre-treatments, abolished, or reduced, the effects of 0.1 and 1.0 μm FPL on cytosolic Ca2+ signals. FPL (1.0 μm) increased the incidence of atrial tachycardia and fibrillation in intact Langendorff-perfused hearts without altering atrial effective refractory periods. These effects were inhibited by nifedipine and caffeine, and reduced by CPA. Conclusion: Enhanced extracellular Ca2+ entry exerts acute atrial arrhythmogenic effects that is nevertheless dependent upon diastolic Ca2+ release. These findings complement reports that associate established, chronic, atrial arrhythmogenesis with decreased overall inward Ca2+ current